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KMID : 0371619940100010093
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Journal of Wonkwang Medical Science
1994 Volume.10 No. 1 p.93 ~ p.100
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2 Cases of Neonatal Tetanus treated with Intermittent Positive-Pressure Ventilation
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Lee Soon-Kil
Oh Jae-Hwa
Oh Yeon-Kyun
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Abstract
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We report 2 cases of neonatal tetanus treated with intermittent positive ventilation(IPPV) combined with neuromuscular blockade and high dose diazepam Duration of mechanical ventilation was ranged from 11 days in case 1 to 19 days in case 2. Muscle relaxation and sedation were achieved by continuous intravenous infusion of high dose diazepam(15-30㎎/㎏/day) and difficult ventilation due to muscle rigidity was removed by Mioblock? . If spasm was severe and frequent, additional bolus injection of Diazepam and Chlorpromazine were administered. Pneumonia with atelectasis were complicated in both cases, but cleared up with susceptible antibiotics and vigorous physiotherapy. We thought that severe neonatal tetanus was best treated by IPPV with Mioblock? and high dose Diazepam. A brief review of the related literature is given.
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